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KMID : 0362919850030020095
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Journal of the Korean Society for Therapeutic Radiology and Oncology
1985 Volume.3 No. 2 p.95 ~ p.101
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The Results of Radiation Treatment in Carcinoma of the Uterine Cervix
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Lee Myung-Za
Kim Jung-Jin
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Abstract
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From July 1979 through March 1985, 112 patients with carcinoma of the uterine cervix were treated by whole pelvis irradiation and intracavitary radiation with Cs-137.
The treatment consisted of 3600rad-5200rad to the whole pelvis by parallel opposing portals, 5 days per week, 180-200rad per day. Parametrial boost with 400-800rad was given in 60 patients. 2 intracavitary Cs-137 radiation using TAO applicator were done with 7-10 days interval. Total treatment times were 40-65 days with average 52 days.
Total dose of radiation to point A varied from 6820 to 10500rad with average 8388rad and to point B from 4850 to 6899rad with average 5898rad.
All patients had follow up from 6 months to 75 months and median follow up of 31 months.
9(8%) had stage Ⅰb, 14(12.5%) had stage Ⅱa, 50(44.6%) had stage llb, 33(29.5%) had stage Ⅲ, 6(5.4%) had stage Ⅳ. 110 patients had squamous cell carcinoma and 2 patients had adenocarcinoma.
5 year actuarial survival rates were 61.8% for the entire group, 84.6% for stage Ⅰb, 77.8% for stage Ⅱa, 56.7% for stage Ⅱb, 60% for stage Ⅲ, 33.3% for stage Ⅳ. RT dose to medial parametrium (point A) below 8000rad resulted in 7/18(38.9%) failure (=death) in contrast to 25/94 (26.5%) failure with dose over 800rad. RT dose to lateral parametrium (point B) below 6000rad yielded 20/63 (34.9%) failure compared to 10/49 (20.4%) failure with dose over 6000rad.
Poor survival group of age were between 40-49 years with failure of 14/41 (34.1%). There was no increased failure rate below age of 40 with failure of 2/11 (13.9%).
The results suggest that survival is as good as other published data, and that higher doses over 8000rad to point A and 6000rad to point B should be delivered.
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KEYWORD
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Carcinoma of the uterine cervix, Radiation treatment, TAO applicator, 5 year acturial survival rate
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